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DeCS
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Descriptor English:
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beta-N-Acetylhexosaminidases
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Descriptor Spanish:
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beta-N-Acetilhexosaminidasas
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Descriptor Portuguese:
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beta-N-Acetil-Hexosaminidases
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Synonyms English:
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N-Acetyl-beta-D-hexosaminidase
beta-Hexosaminidase
beta-N-Acetyl-D-hexosaminidase
beta-N-Acetyl-hexosaminidase
N Acetyl beta D hexosaminidase
beta Hexosaminidase
beta N Acetyl D hexosaminidase
beta N Acetyl hexosaminidase
beta N Acetylhexosaminidase
beta N Acetylhexosaminidases
beta-N-Acetylhexosaminidase
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Tree Number:
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D08.811.277.450.483.180
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Definition English:
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A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease. |
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Indexing Annotation English:
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do not confuse with ACETYLGLUCOSAMINIDASE; /defic: consider also TAY SACHS DISEASE and SANDHOFF DISEASE
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See Related English:
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Sandhoff Disease
Tay-Sachs Disease
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History Note English:
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2008(1988)
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Allowable Qualifiers English:
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Record Number:
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19087
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Unique Identifier:
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D001619
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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